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Erasmus MC – VUmc collaboration discover new gene involved in the development of Parkinson’s disease and dementia with Lewy bodies

An international team led by Prof. Vincenzo Bonifati from the Erasmus MC Rotterdam, Department of Clinical Genetics, has discovered for the first time variants in a gene (termed LRP10) in patients with familial forms of Parkinson’s disease, Parkinson’s disease and dementia, and Dementia with Lewy bodies. The paper reporting this discovery will be published in The Lancet Neurology this week. ‘This discovery opens a novel window on the molecular mechanisms of these common neurodegenerative diseases, and might pave the way to the identification of novel biomarkers and novel disease-modifying therapies’, says Prof. Bonifati.


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