Extensive neuropathological assessment includes evaluation of lesions in cortical, subcortical and brainstem regions using immunohistochemistry, silver staining techniques and histological staining by experienced neuropathologist.
Neuropathological lesions are stained using different techniques including immunohistochemistry, mAG, Bodian, Gallyas and Hematoxylin-Eosin. Multiple cortical and subcortical and brainstem regions are included to stage and score the pathological lesions according to recent guidelines.